Lab Journal Club

Every couple of weeks we have a lab journal club in which we discuss, comment, critique and enjoy (usually!) recent papers in our field. I’ll update with new papers as we discuss them. But here are some of the papers we’ve discussed (and usually liked) over the last year or so:

Biochemical membrane lipidomics during Drosophila development.

Guan XL, Cestra G, Shui G, Kuhrs A, Schittenhelm RB, Hafen E, van der Goot FG, Robinett CC, Gatti M, Gonzalez-Gaitan M, Wenk MR.Dev Cell. 2013 Jan 14;24(1):98-111.

dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth.

Parisi F, Riccardo S, Zola S, Lora C, Grifoni D, Brown LM, Bellosta P.Dev Biol. 2013 Apr 19

A histone mutant reproduces the phenotype caused by loss of histone-modifying factor Polycomb.

Pengelly AR, Copur Ö, Jäckle H, Herzig A, Müller J. Science. 2013 Feb 8;339(6120):698-9.


Transcription in the absence of histone H3.2 and H3K4 methylation.

Hödl M, Basler K.Curr Biol. 2012 Dec 4;22(23):2253-7


The oscillating miRNA 959-964 cluster impacts Drosophila feeding time and other circadian outputs.

Vodala S, Pescatore S, Rodriguez J, Buescher M, Chen YW, Weng R, Cohen SM, Rosbash M.  Cell Metab. 2012 Nov 7;16(5):601-12.


A secreted decoy of InR antagonizes insulin/IGF signaling to restrict body growth in Drosophila.

Okamoto N, Nakamori R, Murai T, Yamauchi Y, Masuda A, Nishimura T. Genes Dev. 2013 Jan 1;27(1):87-97.


Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion.

Rajan A, Perrimon N. Cell. 2012 Sep 28;151(1):123-37


Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster.

Katewa SD, Demontis F, Kolipinski M, Hubbard A, Gill MS, Perrimon N, Melov S, Kapahi P.Cell Metab. 2012 Jul 3;16(1):97-103 


Conserved microRNA miR-8 controls body size in response to steroid signaling in Drosophila.

Jin H, Kim VN, Hyun S.Genes Dev. 2012 Jul 1;26(13):1427-32.


Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP.

Straßburger K, Tiebe M, Pinna F, Breuhahn K, Teleman AA. Dev Biol. 2012 Jul 15;367(2):187-96.


Secreted peptide Dilp8 coordinates Drosophila tissue growth with developmental timing.

Colombani J, Andersen DS, Léopold P. Science. 2012 May 4;336(6081):582-5.


Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation.

Garelli A, Gontijo AM, Miguela V, Caparros E, Dominguez M. Science. 2012 May 4;336(6081):579-82


Direct sensing of systemic and nutritional signals by haematopoietic progenitors in Drosophila.

Shim J, Mukherjee T, Banerjee U. Nat Cell Biol. 2012 Mar 11;14(4):394-400.


Insulin signaling regulates fatty acid catabolism at the level of CoA activation.

Xu X, Gopalacharyulu P, Seppänen-Laakso T, Ruskeepää AL, Aye CC, Carson BP, Mora S, Orešič M, Teleman AA. PLoS Genet. 2012 Jan;8(1):


FOXO regulates organ-specific phenotypic plasticity in Drosophila.

Tang HY, Smith-Caldas MS, Driscoll MV, Salhadar S, Shingleton AW. PLoS Genet. 2011 Nov;7(11)


Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis.

Cognigni P, Bailey AP, Miguel-Aliaga I. Cell Metab. 2011 Jan 5;13(1):92-104.