Papers

Lab Papers (click on journal for link)

  • Sriskanthadevan-Pirahas S, Tinwala AQ, Turingan MJ, Khan S, GREWAL SS (2023).Mitochondrial metabolism in Drosophila macrophage-like cells regulates body growth via modulation of cytokine and insulin signaling. Biorxiv doi.org/10.1101/2023.02.15.528747
  • Deliu LP, Jadir D, Ghosh A, GREWAL SS (2022) Serotonergic neuron ribosomes regulate the neuroendocrine control of Drosophila development PLoS Genetics, 18(9): e1010371.
  • Ding, K., Barretto, E.C., Johnston, M., Lee, B., Gallo, M., and GREWAL SS. (2022). Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila. G3, 12(12):jkac263.
  • Deshpande R, Lee B, GREWAL SS (2022) Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the Immune Deficiency (Imd) signalling pathway. G3, org/10.1093/g3journal/jkac163
  • Sriskanthadevan-Pirahas S, Turingan MJ, Chahal JS, Thorson E, and GREWAL SS (2022) Adipose mitochondrial metabolism controls body growth by modulating systemic cytokine and insulin signaling. Cell Reports 39, 110802.
  • Deshpande R, Lee B, Qiao Y, GREWAL SS. (2022) TOR signalling is required for host lipid metabolic remodelling and survival following enteric infection in Dis Model Mech, 15, dmm049551
  • Marygold, S.J., Alic, N., Gilmour, D.S. & GREWAL SS 2020) In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits. MicroPubl Biol 2020(2020).
  • Polan DM, Alansari M, Lee B, GREWAL SS. (2020) Early-life hypoxia alters adult physiology and reduces stress resistance and lifespan in Drosophila J Exp Biol, 223 (22): jeb226027
  • Barretto EC, Polan DM, Beevor-Potts AN, Lee B, GREWAL SS. (2020) Tolerance to hypoxia is promoted by FOXO regulation of the innate immunity transcription factor NF-κB/Relish in Drosophila. Genetics 215(4):1013-1025.
  • Lee B, Barretto EC, Grewal SS (2019) TORC1 modulation in adipose tissue is required for organismal adaptation to hypoxia in Drosophila. Nature Communications. 10, 1878
  • Sriskanthadevan-Pirahas S, Lee J, Grewal SS (2018)The EGF/Ras pathway controls growth in Drosophila via ribosomal RNA synthesis.  Dev Biol. 439(1):19-29
  • Sriskanthadevan-Pirahas S, Deshpande R, Lee B, and Grewal SS. (2018) Ras/ERK-signalling promotes tRNA synthesis and growth via the RNA polymerase III repressor Maf1 in Drosophila.  PLoS Genetics  Feb 5;14(2):e1007202
  • Deliu LP, Ghosh A, Grewal SS. (2017) Investigation of protein synthesis in Drosophila larvae using puromycin labelling.  Biol Open. 2017 Jun 22. pii: bio.026294
  • Rideout EJ, Narsaiya MS, Grewal SS. (2015) The Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila Body Size. PLoS Genetics. 2015 Dec 28;11(12):e1005683
  • Grewal SS (2015) Why should cancer biologists care about tRNAs? tRNA synthesis, mRNA translation and the control of growth. Biochim Biophys Acta
  • Ghosh A, Rideout EJ, Grewal SS (2014) ­­TIF-IA-dependent regulation of ribosome synthesis in Drosophila muscle is required to maintain systemic insulin signaling and larval growth. PloS Genetics 10(10):e1004750
  • Nagarajan S and Grewal SS (2014) An investigation of nutrient-dependent mRNA translation in Drosophila larvae. Biology Open, 3(11):1020-31
  • Killip LE and Grewal SS (2012) DREF controls tissue and organismal growth in Drosophila downstream of nutrition/TOR signaling. Developmental Biology 2012, 371, 191
  • Rodrigues AB, Ayala-Camargo A, Grewal SS, Reyes-Robles T, Krasny M, Wu DC, Johnston LA, and Bach E. Activated (2012) Stat is a supercompetitor that acts independently of Myc, Yorkie, Wingless and ribosome biogenesis. Development 2012, 139, 4051
  • Grewal SS (2012) Controlling growth and body size – fruit fly physiology points the way. F1000 Reports 4:12
  • Marshall L, Rideout EJ, Grewal SS (2012) Nutrient-TOR dependent regulation of RNA polymerase III controls tissue and organismal growth in Drosophila. EMBO J, 31:1916
  • Rideout EJ, Marshall L, Grewal SS. (2012) Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling Proc Natl Acad Sci U S A. 109(4):1139-44
  • Zielke N, Kim KJ, Tran V, Shibutani ST, Bravo MJ, Nagarajan S, van Straaten M, Woods B, von Dassow G, Rottig C, Lehner CF, Grewal SS, Duronio RJ, Edgar BA (2011) Control of Drosophila endocycles by E2F and CRL4CDT2. Nature, 480, 123.
  • Li L, Edgar B.A.E, Grewal S.S. (2010) Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element. BMC Cell Biology. 11, 7
  • Grewal S.S. (2009) The insulin/TOR pathway in growth and homeostasis: A view from the fly world.  41, 1006.